Members of the lab appear in bold

# denotes equal contribution and * denotes corresponding author

2019

  • Black AJ, Gamarra JR, Giudice J*. (2019). More than a messenger: alternative splicing as a therapeutic target. BBA – Gene Regulatory Mechanisms, in press.
  • Hinkle ER, Wiedner HJ#, Black AJ#, Giudice J*. (2019). RNA processing in skeletal muscle biology and disease. Transcription10 (1): 1-20.
  • Leonardi DB, Anselmino N, Brandani JN, Jaworski FM, Páez AV, Mazaira G, Meiss RP, Nuñez M, Nemirovsky SI, Giudice J, Galigniana M, Pecci A, Gueron G, Vazquez E, Cotignola J. (2019). Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer. International Journal of Molecular Sciences 20 (5): pii: E1006. doi: 10.3390/ijms20051006.

2018

  • Blue RE, Koushik A, Engels N, Wiedner HJ, Cooper TA, Giudice J*. (2018). Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology. International Journal of Biochemistry and Cell Biology  pii: S1357-2725(18)30227-9. doi: 10.1016/j.biocel.2018.10.004.
  • Blue RE, Curry EG#, Engels NM#, Lee EY, Giudice J*. (2018). How alternative splicing affects membrane trafficking. Journal of Cell Science 131(10): pii: jcs216465. doi: 10.1242/jcs.216465.
  • Gueron G, Anselmino N, Chiarella P, Ortiz EG, Lage Vickers S, Paez AV, Giudice J, Contin MD, Leonardi D, Jaworski F, Manzano V, Strazza A, Montagna DR, Labanca E, Cotignola J, D Accorso N, Woloszynska-Read A, Navone N, Meiss RP, Ruggiero R, Vazquez E. (2018). Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis. Cell Death and Disease 9 (2): 140. doi: 10.1038/s41419-017-0147-8.

2017

  • Baralle FE, Giudice J*. (2017). Alternative splicing as a regulator of development and tissue identity. Nature Reviews Molecular Cell Biology 8 (7): 437-451.

– Mentioned in the cover

– Included in the Series: “RNA processing and modifications”

– Included in the Nature Web collection entitled “mRNA splicing: 40 years on”.

  • Giudice J*, Taylor JM*. (2017). Muscle as a paracrine and endocrine organ. Current Opinion in Pharmacology 34: 49-55.

2016

  • Paez AV, Pallavecini C, Schuster F, Valacco MP, Giudice J, Ortiz EG, Anselmino N, Labanca E, Binaghi M, Salierno M, Martí MA, Cotignola JH, Woloszynska-Read A, Bruno L, Levi V, Navone N, Vazquez ES, Gueron G. (2016). Heme oxygenase-1 in the forefront of a multi-molecular network that governs cell–cell contacts and filopodia-induced zippering in prostate cancer. Cell Death and Disease 7 (12): e2527. doi: 10.1038/cddis.2016.433.
  • Giudice J*, Loehr JA, Rodney GG, Cooper TA*. (2016). Alternative splicing of four trafficking genes regulates myofiber structure and skeletal muscle physiology. Cell Reports 17 (8): 1923-33.

 Press release :  1. STAT news -2. ALN magazine -3. UNC-Chapel Hill  -4. Technology.org -5. Bionity -6. Biosciences -7. Science Daily 8. EurekAlert -9. HealthCanal -10. MedicalXpress

  • Giudice J, Xia Z, Li W, Cooper TA. (2016). Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1. Scientific Reports 6:35550. doi:10.1038/srep35550.

2015

  • Labanca E, De Luca P, Gueron G, Páez A, Moiola CP, Massillo C, Porretti J, Giudice J, Zalazar F, Navone N, Vazquez E, De Siervi A. (2015). Association of HO-1 and BRCA1 Is Critical for the Maintenance of Cellular Homeostasis in Prostate Cancer. Molecular Cancer Research 3 (11): 1455-64.

 Article selected for the Highlights’s section

  • Wang ET, Ward AJ, Cherone JM, Giudice J, Wang TT, Treacy DJ, Lambert NJ, Freese P, Saxena T, Cooper TA, Burge CB. (2015). Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins. Genome Research 25 (6): 858-71.
  • Pedrotti S, Giudice J, Dagnino-Acosta A, Knoblauch M, Mo Q, Hicks J, Hamilton S, Cooper TA. (2015). The RNA-binding protein Rbfox1 regulates adult skeletal muscle function. Human Molecular Genetetics 4 (8): 2360-74.

2014

  • Giudice J, Xia Z, Wang ET, Ruddy MA, Ward AJ, Kalsotra A, Wang W, Wehrens XHT, Burge CB, Li W, Cooper TA. (2014). Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development. Nature Communications 5: 3603. doi: 10.1038/ncomms4603.

Press release: 1. Baylor College of Medicine -2. ScienceDaily

  • Giudice J*, Cooper TA*. (2014). RNA binding proteins in heart development. Adv Exp Med Biol 825: 389-429.
  • Gueron G*, Giudice J, Elguero B, Valacco P, Paez A, Toscani AM, Jaworski F, Leskow FC, Cotignola J, Marti M, Binaghi M, Navone N, Vazquez E*. (2014). HO-1: the mastermind behind the morphology and the adhesive behavior of prostate cancer cells. Oncotarget 5 (12): 4087-102.

2013

  • Giudice J, Jares-Erijman EA, Leskow FC. (2013). Insulin receptor membrane retention by a traceable chimeric mutant. Cell Communication and Signaling 11(1): 45. doi: 10.1186/1478-811X-11-45.
  • Giudice J, Jares-Erijman E, Leskow FC. (2013). Endocytosis and intracellular dissociation rates of human insulin-insulin receptor complexes by quantum dots in living cells. Bioconjugate Chemistry 24 (3): 431-42.
  • Giudice J, Barcos LS, Guaimas FF, Penas A, Giordano L, Jares-Erijman EA, Leskow FC. (2013). Insulin and IGF-II endocytosis and signaling via insulin receptor B. Cell Communication and Signaling 11 (1): 18. doi: 10.1186/1478-811X-11-18.
  • Pistone Creydt V, Fletcher SJ, Giudice J, Bruzzone A, Chasseing NA, Gonzalez EG, Sacca PA, Calvo JC. (2013). Human adipose tissue from normal and tumoral breast regulates the behaviour of mammary epithelial cells. Clinical Translational Oncology 15 (2): 124-31.

2012

  • Elguero B, Gueron G, Giudice J, Toscani AM, De Luca P, Zalazar F, Leskow FC, Meiss R, Navone N, De Siervi A, Vazquez E. (2012). Heme oxygenase 1 (HO-1) impairs androgen receptor transcription through STAT3 signaling in prostate cancer. Neoplasia 14 (11): 1043-56.

2011

  • Ferrando M#, Gueron G#, Elguero B, Giudice J, Salles A, Leskow FC, Jares-Erijman EA, Colombo L, Meiss R, Navone N, De Siervi A, Vazquez E. (2011). Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer. Angiogenesis 14 (4): 467-79.

2008

  • Rossetti MV, Granata BX, Giudice J, Parera VE, Batlle A. (2008). Genetic and biochemical studies in Argentinean patients with variegate porphyria. BMC Medical Genetics 9 (1): 54. doi: 10.1186/1471-2350-9-54.
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