Lab Manager

Department of Cell Biology and Physiology, School of Medicine

2016 May–

Contact information

6330 Medical Biomolecular Research Building

111 Mason Farm Rd., Chapel Hill, NC 27599

Phone: 919-962-6290


Education and training

Research Specialist, UNC School of Medicine, Cell Biology and Physiology Department, 06/2010-present

M.Sc. Biology, College of William and Mary, Williamsburg, VA, 08/2006-08/2009

B.Sc. Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 08/2001-05/2005


  • Wiedner HJ, Blue RE, Sadovsky M, Mills CA, Wehrens XT, Herring LE, Giudice J. (2023). RBFOX2 regulated EYA3 isoforms partner with SIX4 or ZBTB1 to control transcription during myogenesis. iScience. 26 (11): 108258. doi: 10.1016/j.isci.2023.108258.
  • Hinkle ER, Blue RE, Tsai, Y-H, Combs M, Davi J, Coffey AR, Boriek A, Taylor JM, Parker J, Giudice J. (2022). Mechanical stretching induces global transcriptional and posttranscriptional transitions and changes in SR proteins in muscle cells. Communications Biology. 5 (1): 987. doi: 10.1038/s42003-022-03915-7.
  • Gentile GM#, Gamarra J#, Engels N#, Blue RE#, Hoerr I, Wiedner HJ, Hinkle ER, Cote JL, Leverence E, Mills A, Herring L, Tan X, Giudice J. (2022). The synaptosome-associated protein 23 (SNAP23) is necessary for proper myogenesis. FASEB Journal. 36 (8): e22441. doi: 10.1096/fj.202101627RR. # co-first authors.
  • Wiedner HJ, Torres EV, Blue RE, Tsai YH, Parker J, Giudice J. (2022). SET domain containing 2 (SETD2) influences metabolism and alternative splicing during myogenesis. FEBS Journal. 289 (21): 6799-6816.
  • Hinkle ER#, Wiedner HJ#, Torres E, Jackson M, Black AJ, Blue RE, Harris SE, Guzman BB, Gentile GM, Lee EY, Tsai Y-H , Parker J, Dominguez D, Giudice J. (2022). Alternative splicing regulation of membrane trafficking genes during myogenesis. RNA, 28 (4): 523-540. # co-first authors.
  • Smith JA#, Curry EG#, Blue RE#, Roden C, Dundon SER, Rodriguez-Vargas A, Jordan DC, Chen X, Lyons SM, Crutchley J, Anderson P, Horb M, Gladfelter AS*, Giudice J*. (2020). FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells. Journal of Cell Biology, 219 (4): e201911129. [#equal contribution]
  • Blue RE, Koushik A, Engels N, Wiedner HJ, Cooper TA, Giudice J. (2018). Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology. International Journal of Biochemistry and Cell Biology  pii: S1357-2725(18)30227-9. doi: 10.1016/j.biocel.2018.10.004.
  • Blue RE, Curry EG#, Engels NM#, Lee EY, Giudice J. (2018). How alternative splicing affects membrane trafficking. Journal of Cell Science 131(10): pii: jcs216465. doi: 10.1242/jcs.216465. [#equal contribution]
  • Ding S, Blue RE, Moorefield E, Yuan H, Lund PK. (2017). Ex vivo and in vivo noninvasive imaging of epidermal growth factor receptor inhibition on colon tumorigenesis using activatable near-infared fluorescent probes. Molecular Imaging, 16: 1-13.
  • Moorefield EC, Andres SF, Blue RE, Van Landeghem L, Mah AT, Santoro MA, Ding S. (2017). Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells. Aging (Albany NY), 9(8): 1898-1915.
  • Kechele DO, Blue RE, Zwarycz B, Espenschied ST, Mah AT, Perou CM, Ding S, Magness ST, Lund PK, Caron KM.(2017). Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest,127(2): 593-607.
  • Santoro MA, Blue RE, Andres SF, Mah AT, Van Landeghem L, Lund PK. (2015). Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon. Am J Physiol Gastrointest Liver Physiol, 309(7): G578-89.
  • Andres SF, Santoro MA, Mah AT, Keku JA, Bortvedt AE, Blue RE, Lund PK.(2015).Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs. Am J Physiol Gastrointest Liver Physiol, 308(2): G100-11.
  • Ding S, Blue RE, Morgan DR, Lund PK. (2014). Comparison of multiple enzyme activatable near-infrared fluorescent molecular probes for detection and quantification of inflammation in murine colitis models. Inflamm Bowel Dis, 20(2): 363-77.
  • Van Landeghem L, Blue RE, Dehmer JJ, Henning SJ, Helmrath MA, Lund PK. (2012). Localized intestinal radiation and liquid diet enhance survival and permit evaluation of long-term intestinal responses to high dose radiation in mice. PLoS One, 7(12): e51310.
  • Ding S, Blue ER, Chen Y, Scull B, Kay Lund P, Morgan D. (2015). Molecular imaging of gastric neoplasia with near-infrared fluorescent activatable probes. Mol Imaging, 11(6): 507-15.
  • Ding S, Walton KL, Blue RE, McNaughton K, Magness ST, Lund PK. (2012). Mucosal healing and fibrosis after acute or chronic inflammation in wild type FVB-N mice and C57BL6 procollagen α1(I)-promoter-GFP reporter mice. PLoS One, 7(8): e42568.
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